![]() ![]() If the lesion also involves part of the non-tapetal fundus the overlying retinal pigment epithelium lacks pigment. CH/CRD, referred to as CH in this paper, is characterized by the focal absence of pigmented choroidal tissue and tapetum temporal to the optic disc and the presence of choroidal blood vessels abnormal in both appearance and arrangement. This report demonstrates that Collie Eye Anomaly is present in a Polish bred Australian Kelpie line and as such breeders in this country and those importing dogs or semen internationally should be aware of other possible cases.Ĭollie Eye Anomaly (CEA) is a congenital canine pleomorphic ocular disease characterized by two main lesions, choroidal hypoplasia/chorioretinal dysplasia (CH/CRD) and papillary/peripapillary colobomata. Twenty one other related dogs were subsequently examined genetically, the dam proving to be affected and eight others were shown to be carriers. The DNA based test for the NHEJ1 gene mutation that is confirmatory for Collie Eye Anomaly proved the dog to be homozygous for this mutation. These lesions had the appearance of the choroidal hypoplasia diagnostic for Collie Eye Anomaly, a genetically determined disease seen most commonly in Collie types. Indirect ophthalmoscopy revealed tigroid fundi bilaterally with areas of abnormally arranged choroidal vasculature temporal to the optic disc. ![]() Case presentationsĬhoroidal hypoplasia (CH) was initially diagnosed in a young female Australian Kelpie presented for routine ophthalmological examination prior to breeding. ![]() To report the occurrence of choroidal hypoplasia in the Australian Kelpie breed in Poland, the affected dogs testing positive for the Collie Eye Anomaly NHEJ1 gene mutation. ![]()
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